Correlation Between Hyaluronic Acid,Hyaluronic Acid Synthase And Human Renal Clear Cell Carcinoma

期刊名字：中国癌症研究
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论文作者：Jian-liang Cai，Ming Li，Yan-qun
作者单位：Peking University Wu Jieping Urological Center,Key laboratory of Corcinogenesis and Translational ResearchMinistry of Ed
更新时间：2022-12-23
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论文简介

Objective:To study the correlation between hyaluronic acid(HA),hyaluronic acid synthase(HAS)and human renal clear cell carcinoma(RCCC).Methods:The expression of three HAS isoforms' gene and HA in 93 RCCC tissues,27 nephridial tissues by the side of RCCC from two hospitals were measured with Real-Time RT PCR.Western Blot and immunohistochemical methods and analyzed.Results:All RCCC and adjacent normal tissues expressed three HASs' mRNA & protein;at the mRNA level,both RCCC and adjacent normal tissues,expressed more HAS3 than HAS1 or HAS2,their differences were statistically significant(all P values

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