Synthesis of Heterocycle Compounds Containing Two Pyridazinone Units

Four novel compounds containing two pyridazinone units attached to one benzene or pyridine ring,protected and deprotected 1,5-di[3(2H)-pyridazinon-6-yl]benzene and 2,6-di[3(2H)-pyridazinon-6-yl]pyridine were synthesized in eight steps,which provided a useful method for the preparation of pyridazinone derivatives via the Stetter and cyclization reactions.Their structures were characterized by 1H NMR,13CNMR and HRMS.