管内固相微萃取-气相色谱法在线联用技术用于水样中的痕量分析

Since the development of solid phase micro-extraction (SPME) method[1], many modifications have been made to improve the availability and application of the technique[2-5]. The in-tube SPME (ITSPME) was emerged and employed in high performance liquid chromatography (HPLC) as an efficient and simple preparation method, which offers several advantages over the fiber SPME syringe[6]. The ITSPME should preserve the advantages of SPME, and could offer higher enrichment factor, better quantitation, and automation through an on-line coupling with a chromatograph.