Synthesis and Herbicidal Activity of Novel Sulfonylurea Derivatives

Suifonylurea herbicides have been applied worldwide in agriculture.Some sulfonylurea residues might exist in soil longer than that people expected.However,flupyrsulfuron-methyl-sodium which was firstly reported as a new 5-substituted sulfonylurea herbicide has less than one month residual life.Therefore,5-substituted benzenesulfonylureas are potential molecules to regulate its residual situation.In order to develop new sulfonylurea derivatives,the substituent on the critical 5-posotion of the benzene ring was optimized.On the basis of our former work on sulfonylureas which contains a characteristic mono-substituted pyrimidine moiety,twenty-six new suifonylurea derivatives were synthesized and their structures were confirmed by 1H NMR,31P NMR and elemental analysis.The greenhouse bioassay tests show that some title compounds exhibit potent herbicidal activity.