Facile Synthesis and Crystal Structure of a Novel Cyanopyridine

The title compound 2-amino-4-(4-hydroxy-3,5-dimethoxyphenyl)-5-methyl-6-phenyl nicotinonitrile, CHNO,was synthesized via four-component reactions between propio-phenone, malononitrile, syringaldehyde and ammonium acetate in ethanol under reflux without catalyst and characterized by IR, C NMR, MS, EA and single-crystal X-ray diffraction.Single-crystal X-ray diffraction analysis shows that the compound is of monoclinic system, space group P2/n with a = 8.4600(17), b = 17.139(3), c = 13.408(3) A,β= 107.06(3)°, V= 1858.6(6) A, Dc = 1.292 g/cm