首页 > 资料下载 > 金属与颗粒物结合对 人肺上皮细胞Effects of Metals Bound to Particulate Matter on Human Lung Epithelial Cells
金属与颗粒物结合对 人肺上皮细胞Effects of Metals Bound to Particulate Matter on Human Lung Epithelial Cells 金属与颗粒物结合对 人肺上皮细胞Effects of Metals Bound to Particulate Matter on Human Lung Epithelial Cells

金属与颗粒物结合对 人肺上皮细胞Effects of Metals Bound to Particulate Matter on Human Lung Epithelial Cells

  • 资料类别:
  • 资料大小:
  • 资料编号:
  • 资料状态:
  • 更新时间:2021-09-09
  • 下载次数:
资料简介

吸入颗粒物与急性和慢性健康影响有关。对这些影响的关注主要来自流行病学研究,这些研究将短期内颗粒物浓度的增加与呼吸系统和心血管疾病的每日发病率和死亡率的增加联系起来。在过去的十年中,许多研究都致力于确定颗粒物与病理生理效应之间的可能机制。虽然已经取得了进展,但许多关键方面还不清楚。因此,对可能诱发病理效应的颗粒性质的研究对于建立颗粒物毒性机制和产生必要的信息来调节产生毒性最强的颗粒的源极是至关重要的。使用实验室动物进行的研究表明,与颗粒物相关的金属会对健康产生不良影响。燃煤电厂产生的颗粒物残渣称为粉煤灰。煤中含有的金属在燃烧过程中蒸发,然后在灰烬表面凝结。吸入粉煤灰可能是一种健康危害,因为金属从飞灰溶解在肺细胞内可能会引起毒性反应。

Inhaled particulate matter has been associated with both acute and chronic health effects. Concerns about these effects derive primarily from epidemiologic studies that associate short-term increases in particle concentration with increases in daily morbidity and mortality from respiratory and cardiovascular diseases. Over the past decade much research has been directed toward identifying plausible mechanisms linking particulate matter and pathophysiologic effects. Although progress has been made, many critical aspects are not understood. Thus, studies of the properties of particles that might induce pathologic effects are critical to establishing the mechanisms of particulate matter toxicity and to producing information necessary to target regulation of the sources that generate the most toxic particles. Studies using laboratory animals have implicated metals associated with particulate matter in adverse health effects. Coal-fired power plants produce particulate residues called fly ash. Coal contains metals that vaporize during combustion and then condense on the surface of the ash. Inhaled coal fly ash could be a health hazard because metals solubilized from fly ash within lung cells may cause toxic reactions.

资料截图
版权:如无特殊注明,文章转载自网络,侵权请联系cnmhg168#163.com删除!文件均为网友上传,仅供研究和学习使用,务必24小时内删除。